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Compound Detail

CHEMBL448901

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[O-][N+]1=C(C2=C[C@@]3(O)CC/C=C\CCCCN4CC[C@@H]2[C@]2(CC5/C=C\CCCCN5[C@H]23)C4)c2[nH]c3ccccc3c2CC1

Basic Information

ChEMBL ID CHEMBL448901
Phase Preclinical
Structure Type MOL
InChI Key SPQVJBJQVWOEOF-SLKXIYNCSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

566.8
MW (Da)
5.71
ALogP
4
HBA
2
HBD
68.6
PSA (Ų)
0.26
QED
2
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C36H46N4O2
MW 566.79
Aromatic Rings 2
Heavy Atoms 42
NP-Likeness 2.20

Literature References

PubMed DOI Target Context # Activities
15332848 10.1021/np0400095 Staphylococcus aureus 2
15332848 10.1021/np0400095 Vero 1
15332848 10.1021/np0400095 Cryptococcus neoformans 1
15332848 10.1021/np0400095 Mycobacterium intracellulare 1
15332848 10.1021/np0400095 Human immunodeficiency virus 1 1
15332848 10.1021/np0400095 Mycobacterium tuberculosis 1
34332400 10.1016/j.ejmech.2021.113688 L5178Y 1

Data from ChEMBL 36 via Core Engine