Compound Detail
CHEMBL448964
PROCOCENE II Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL448964 |
| Name | PROCOCENE II |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PTIDGSWTMLSGAH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
15
Publications
0
Known Names
Molecular Properties
220.3
MW (Da)
2.89
ALogP
3
HBA
0
HBD
27.7
PSA (Ų)
0.77
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fusarium graminearum CHEMBL2366834 | IC50 | 5.92 | 5.92 | 1200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fusarium graminearum | IC50 | = | 1200.0 | nM | 5.92 | Inhibition of 3-acetyldeoxynivalenol production by Fusarium graminearum in liqui... | 19191669 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19191669 | 10.1021/jf802813h | Fusarium graminearum | 11 |
| 16028972 | 10.1021/jf058034j | Leptinotarsa decemlineata | 6 |
| 16028972 | 10.1021/jf058034j | Tribolium confusum | 6 |
| - | 10.1584/jpestics.16.267 | Oncopeltus fasciatus | 4 |
| 16028972 | 10.1021/jf058034j | Sitophilus granarius | 3 |
| 16028972 | 10.1021/jf058034j | Trogoderma granarium | 3 |
| - | 10.1021/np50027a006 | Saccharomyces cerevisiae | 1 |
| - | 10.1021/np50027a006 | Candida albicans | 1 |
| - | 10.1021/np50027a006 | Escherichia coli | 1 |
| - | 10.1021/np50027a006 | Pseudomonas fluorescens | 1 |
| - | 10.1021/np50027a006 | Bacillus subtilis | 1 |
| - | 10.1021/np50027a006 | Staphylococcus | 1 |
| - | 10.1021/np50027a006 | Oncopeltus fasciatus | 1 |
| 16028972 | 10.1021/jf058034j | Aphididae | 1 |
| - | 10.1584/jpestics.16.267 | Pieris brassicae | 1 |
Data from ChEMBL 36 via Core Engine