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Compound Detail

CHEMBL450482

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CC1=CC[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C[C@@H](OS(=O)(=O)O)[C@H](C)CCC/C(C)=C/Cc1cc(O)ccc1O.CN(C)C(=N)N

Basic Information

ChEMBL ID CHEMBL450482
Phase Preclinical
Structure Type MOL
InChI Key PGXCZDFDIRBXDW-NHDYRKAGSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names

Molecular Properties

635.9
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C34H57N3O6S
MW 635.91

Activity Summary

IC50 2 meas.

Literature References

PubMed DOI Target Context # Activities
18824352 10.1016/j.bmcl.2008.09.059 Isocitrate lyase 1
18824352 10.1016/j.bmcl.2008.09.059 Candida albicans 1
18824352 10.1016/j.bmcl.2008.09.059 Staphylococcus aureus 1
18824352 10.1016/j.bmcl.2008.09.059 Bacillus subtilis 1
18824352 10.1016/j.bmcl.2008.09.059 Micrococcus luteus 1
18824352 10.1016/j.bmcl.2008.09.059 Proteus vulgaris 1
18824352 10.1016/j.bmcl.2008.09.059 Salmonella typhimurium 1
18824352 10.1016/j.bmcl.2008.09.059 Escherichia coli 1

Data from ChEMBL 36 via Core Engine