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Compound Detail

CHEMBL4517551

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Nc1cc(Cl)nc(N)n1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4517551
Phase Preclinical
Structure Type MOL
InChI Key QJIUMVUZDYPQRT-UHFFFAOYSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

144.6
MW (Da)
0.29
ALogP
4
HBA
2
HBD
77.8
PSA (Ų)
0.51
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C4H5ClN4
MW 144.56
Aromatic Rings 1
Heavy Atoms 9
NP-Likeness -0.89

Activity Summary

Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
26908025 10.1021/acs.jmedchem.5b01813 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 1

Data from ChEMBL 36 via Core Engine