Compound Detail
CHEMBL451971
ISODEHYDROCOSTUS LACTONE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL451971 |
| Name | ISODEHYDROCOSTUS LACTONE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HOKNRQOXIXGZDY-XUXIUFHCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
230.3
MW (Da)
3.02
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.36
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.8 | 4.8 | 16000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 16000.0 | nM | 4.8 | Inhibition of killing activity of CD8+ specific mouse CTL-OE4 cells | 9917276 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9917276 | 10.1021/np980092u | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine