Compound Detail
CHEMBL4536216
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Basic Information
| ChEMBL ID | CHEMBL4536216 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | USICCXHZKWZTMY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
239.3
MW (Da)
2.25
ALogP
2
HBA
1
HBD
38.3
PSA (Ų)
0.87
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.74
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melatonin receptor type 1C CHEMBL5495 | EC50 | 8.74 | 8.74 | 1.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melatonin receptor type 1C | EC50 | = | 1.82 | nM | 8.74 | Agonist activity at Melatonin receptor type 1C in Xenopus laevis melanophores as... | 31191854 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31191854 | 10.1039/C8MD00604K | Melatonin receptor type 1C | 3 |
Data from ChEMBL 36 via Core Engine