Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL4545962

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H](O)[C@@]1(F)Br
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4545962
Phase Preclinical
Structure Type MOL
InChI Key JTUCAFQVRHFYFB-TWJUVVLDSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

348.1
MW (Da)
-0.28
ALogP
8
HBA
3
HBD
119.3
PSA (Ų)
0.64
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H11BrFN5O3
MW 348.13
Aromatic Rings 2
Heavy Atoms 20
NP-Likeness 0.84

Literature References

PubMed DOI Target Context # Activities
30653317 10.1021/acs.jmedchem.8b01300 RNA-directed RNA polymerase 2
30653317 10.1021/acs.jmedchem.8b01300 Huh-7 1
30653317 10.1021/acs.jmedchem.8b01300 PBMC 1
30653317 10.1021/acs.jmedchem.8b01300 CCRF-CEM 1
30653317 10.1021/acs.jmedchem.8b01300 Vero 1

Data from ChEMBL 36 via Core Engine