Compound Detail
CHEMBL4547685
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Basic Information
| ChEMBL ID | CHEMBL4547685 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NGKDECHJIUPPDL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
360.5
MW (Da)
2.91
ALogP
5
HBA
0
HBD
49.3
PSA (Ų)
0.84
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cholesterol 24-hydroxylase CHEMBL4523510 | IC50 | 8.31 | 8.31 | 4.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cholesterol 24-hydroxylase | IC50 | = | 4.9 | nM | 8.31 | Inhibitory Assay: For the measurement of CH24H inhibitory activity, using the hu... | - |
Data from ChEMBL 36 via Core Engine