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Compound Detail

CHEMBL4547767

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Nc1cc(C(F)(F)F)ccc1NC(=O)Nc1cccc(S(=O)(=O)NCCCC(=O)O)c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4547767
Phase Preclinical
Structure Type MOL
InChI Key MUIXXDLSFQTARW-UHFFFAOYSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

460.4
MW (Da)
3.07
ALogP
5
HBA
5
HBD
150.6
PSA (Ų)
0.30
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H19F3N4O5S
MW 460.43
Aromatic Rings 2
Heavy Atoms 31
NP-Likeness -1.78

Activity Summary

IC50 2 meas.

Literature References

PubMed DOI Target Context # Activities
30368131 10.1016/j.ejmech.2018.09.056 Nonstructural protein 5 1
30368131 10.1016/j.ejmech.2018.09.056 Genome polyprotein 1

Data from ChEMBL 36 via Core Engine