Compound Detail
CHEMBL4563574
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Basic Information
| ChEMBL ID | CHEMBL4563574 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GMADMWOUOOIIHH-IBGZPJMESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
366.5
MW (Da)
3.43
ALogP
6
HBA
1
HBD
54.2
PSA (Ų)
0.77
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 CHEMBL4980 | Ki | 9.7 | 9.7 | 0.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 | Ki | = | 0.2 | nM | 9.7 | Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain ... | 31271958 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31271958 | 10.1016/j.ejmech.2019.06.049 | Neuronal acetylcholine receptor subunit alpha-7 | 1 |
Data from ChEMBL 36 via Core Engine