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Compound Detail

CHEMBL4581801

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O=C1CC(NC(=O)Cc2ccccc2)C(=O)N1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4581801
Phase Preclinical
Structure Type MOL
InChI Key ZTMDMWMWWGOUHX-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

232.2
MW (Da)
-0.24
ALogP
3
HBA
2
HBD
75.3
PSA (Ų)
0.71
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C12H12N2O3
MW 232.24
Aromatic Rings 1
Heavy Atoms 17
NP-Likeness -0.48

Literature References

PubMed DOI Target Context # Activities
31251063 10.1021/acs.jmedchem.9b00454 Cereblon isoform 4 1
31251063 10.1021/acs.jmedchem.9b00454 Cereblon/Casein kinase I alpha 1
31251063 10.1021/acs.jmedchem.9b00454 Protein cereblon/Aiolos 1

Data from ChEMBL 36 via Core Engine