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Compound Detail

CHEMBL4590792

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O=C[C@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H](O)[C@H](O)[C@H](O)CO

Basic Information

ChEMBL ID CHEMBL4590792
Phase Preclinical
Structure Type MOL
InChI Key PZDOWFGHCNHPQD-OQPGPFOOSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

342.3
MW (Da)
-5.55
ALogP
11
HBA
8
HBD
197.4
PSA (Ų)
0.20
QED
2
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C12H22O11
MW 342.30
Aromatic Rings 0
Heavy Atoms 23
NP-Likeness 2.19

Activity Summary

EC50 1 meas. best 6.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Olfactory receptor 51E2
CHEMBL4523454
EC50 6.0 6.0 1000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Olfactory receptor 51E2 EC50 = 1000.0 nM 6.0 Agonist activity at PSGR/OR51E2 (unknown origin) expressed in human Hana3A cells... -

Data from ChEMBL 36 via Core Engine