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Compound Detail

CHEMBL4594406

LUTETIUM LU-177 VIPIVOTIDE TETRAXETAN
💊 Approved Drug
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💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL4594406
Name LUTETIUM LU-177 VIPIVOTIDE TETRAXETAN
Phase Approved
Structure Type NONE
Therapeutic ✓ Yes
Parent Compound CHEMBL4594730
Active Moiety CHEMBL4594730

Known Names

177LU-LABELED PSMA-617 177lu-psma-617 Lutetium (177lu) vipivotide tetraxetan Lutetium lu 177 vipivotide tetraxetan Lutetium lu-177 vipivotide tetraxetan Pluvicto Psma-617 lu-177 Vipivotide tetraxetan lu-177 Vipivotide tetraxetan lutetium lu-177
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
9
Known Names
8
Indications
2
Mechanisms

Molecular Properties

1214.1
MW (Da)

Drug Information

Molecule Type Protein
First Approval 2022
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

First in Class
USAN Stem -tide; -xetan
USAN Year 2021

Extended Properties

Molecular Formula C49H68LuN9O16
MW 1216.07

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Glutamate carboxypeptidase II binding agent BINDING AGENT Glutamate carboxypeptidase 2
DNA disrupting agent DISRUPTING AGENT DNA

Indications

Prostatic Neoplasms, Castration-Resistant Prostatic Neoplasms, Castration-Resistant Prostatic Neoplasms Prostatic Neoplasms Prostatic Neoplasms Carcinoma, Adenoid Cystic Urogenital Neoplasms Neoplasms

ATC Classification

V10XX05
lutetium (177Lu) vipivotide tetraxetan
Level 1: VARIOUS
Level 2: THERAPEUTIC RADIOPHARMACEUTICALS

Data from ChEMBL 36 via Core Engine