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Compound Detail

CHEMBL4594607

APADAMTASE ALFA
💊 Approved Drug
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💊 Approved Drug
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ChEMBL ↗

Basic Information

ChEMBL ID CHEMBL4594607
Name APADAMTASE ALFA
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

Adamts13 q23, recombinant Adamts13 q23, recombinant human Adamts13, recombinant human Adzynma Apadamtasa alfa Apadamtase alfa BAX 930 BAX-930 Bax930 Native radamts13 q23 RADAMTS-13 RADAMTS-13 Q23 +8 more
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
20
Known Names
3
Indications
1
Mechanisms

Drug Information

Molecule Type Enzyme
First Approval 2023
Availability Prescription
Chirality Single Enantiomer
USAN Stem -ase
USAN Year 2022

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
A disintegrin and metalloproteinase with thrombospondin motifs 13 exogenous protein EXOGENOUS PROTEIN A disintegrin and metalloproteinase with thrombospondin motifs 13 ✓ ✓

Indications

Purpura, Thrombotic Thrombocytopenic Purpura, Thrombotic Thrombocytopenic Anemia, Sickle Cell

Data from ChEMBL 36 via Core Engine