Compound Detail
CHEMBL4597203
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Basic Information
| ChEMBL ID | CHEMBL4597203 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VISDQYOXQLXIFC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
319.4
MW (Da)
3.01
ALogP
4
HBA
3
HBD
88.2
PSA (Ų)
0.69
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysine-specific demethylase 6A CHEMBL2069164 | IC50 | 4.57 | 4.57 | 27000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysine-specific demethylase 6A | IC50 | = | 27000.0 | nM | 4.57 | Inhibition of human UTX using Biotin-KAPRKQLATKAARK(me3)SAPATGG as substrate by ... | 38214982 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38214982 | 10.1021/acs.jmedchem.3c02133 | Lysine-specific histone demethylase 1A | 1 |
| 38214982 | 10.1021/acs.jmedchem.3c02133 | Lysine-specific demethylase 6A | 1 |
Data from ChEMBL 36 via Core Engine