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Compound Detail

CHEMBL461910

ASPERULOSIDE
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CC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]1[C@@H]32

Basic Information

ChEMBL ID CHEMBL461910
Name ASPERULOSIDE
Phase Preclinical
Structure Type MOL
InChI Key IBIPGYWNOBGEMH-DILZHRMZSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

414.4
MW (Da)
-2.30
ALogP
11
HBA
4
HBD
161.2
PSA (Ų)
0.28
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C18H22O11
MW 414.36
Aromatic Rings 0
Heavy Atoms 29
NP-Likeness 2.86

Literature References

PubMed DOI Target Context # Activities
21324693 10.1016/j.bmcl.2011.01.060 Mus musculus 9
15844957 10.1021/np0495985 NON-PROTEIN TARGET 2
35489224 10.1016/j.ejmech.2022.114405 Mus musculus 2
11473436 10.1021/np000614h NON-PROTEIN TARGET 1
15844957 10.1021/np0495985 Radical scavenging activity 1
27509358 10.1021/acs.jnatprod.6b00484 Pancreatic alpha-amylase 1
35489224 10.1016/j.ejmech.2022.114405 Rattus norvegicus 1

Data from ChEMBL 36 via Core Engine