Compound Detail
CHEMBL4630641
A-769 Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL4630641 |
| Name | A-769 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CWIBKFSDMFUDFD-UHFFFAOYSA-N |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
20
Publications
1
Known Names
Molecular Properties
339.5
MW (Da)
3.00
ALogP
5
HBA
1
HBD
48.0
PSA (Ų)
0.74
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4507260 | Tyrosine-protein kinase ABL1 | 15 |
| - | 10.6019/CHEMBL5724558 | Colon cancer organoid | 12 |
| - | 10.6019/CHEMBL5674860 | Colon cancer organoid | 12 |
| - | 10.6019/CHEMBL4507260 | Epidermal growth factor receptor | 12 |
| - | 10.6019/CHEMBL4507260 | Receptor-type tyrosine-protein kinase FLT3 | 11 |
| - | 10.6019/CHEMBL4689842 | Fibroblast | 10 |
| - | 10.6019/CHEMBL4507260 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 10 |
| - | 10.6019/CHEMBL4689842 | HEK-293T | 10 |
| - | 10.6019/CHEMBL4507260 | Mast/stem cell growth factor receptor Kit | 9 |
| - | 10.6019/CHEMBL4689842 | U2OS | 8 |
| - | 10.6019/CHEMBL4507260 | Unchecked | 7 |
| - | 10.6019/CHEMBL5608141 | Colon cancer organoid | 6 |
| - | 10.1158/2159-8290.CD-23-0050 | Colon cancer organoid | 5 |
| - | 10.6019/CHEMBL4507260 | Proto-oncogene tyrosine-protein kinase receptor Ret | 4 |
| - | 10.6019/CHEMBL4507260 | Hepatocyte growth factor receptor | 3 |
| - | 10.6019/CHEMBL4507260 | ALK tyrosine kinase receptor | 3 |
| - | 10.6019/CHEMBL4507260 | Ribosomal protein S6 kinase alpha-4 | 2 |
| - | 10.6019/CHEMBL4507260 | Ribosomal protein S6 kinase alpha-1 | 2 |
| - | 10.6019/CHEMBL4507260 | Tyrosine-protein kinase JAK1 | 2 |
| - | 10.6019/CHEMBL4507260 | Ribosomal protein S6 kinase alpha-5 | 2 |
Data from ChEMBL 36 via Core Engine