Compound Detail
CHEMBL4636888
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Basic Information
| ChEMBL ID | CHEMBL4636888 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | STTALFHVLYDPIH-AUWJEWJLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
346.1
MW (Da)
3.97
ALogP
4
HBA
0
HBD
69.4
PSA (Ų)
0.47
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| K562 CHEMBL385 | IC50 | 6.43 | 6.43 | 370.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| K562 | IC50 | = | 370.0 | nM | 6.43 | Cytotoxicity against human K562 cells assessed as reduction in cell viability by... | 30739824 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30739824 | 10.1016/j.ejmech.2019.01.078 | K562 | 1 |
Data from ChEMBL 36 via Core Engine