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Compound Detail

CHEMBL4639001

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Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccccc2Cl)on1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4639001
Phase Preclinical
Structure Type MOL
InChI Key UGZKBQSCCGQTLZ-CJNGLKHVSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

377.8
MW (Da)
1.46
ALogP
5
HBA
2
HBD
95.7
PSA (Ų)
0.82
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H20ClN3O4
MW 377.83
Aromatic Rings 2
Heavy Atoms 26
NP-Likeness -1.53

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
32142281 10.1021/acs.jmedchem.9b01451 von Hippel-Lindau disease tumor suppressor 1

Data from ChEMBL 36 via Core Engine