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Compound Detail

CHEMBL4642134

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CC(=O)O[C@H]1[C@@H](OC(C)=O)C[C@H](O[C@H]2[C@@H](OC(C)=O)C[C@H](O[C@H]3[C@@H](OC(C)=O)C[C@H](O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](OC(C)=O)[C@]5(C)[C@@H](C7=CC(=O)OC7)CC[C@]65O)C4)O[C@@H]3C)O[C@@H]2C)O[C@@H]1C

Basic Information

ChEMBL ID CHEMBL4642134
Phase Preclinical
Structure Type MOL
InChI Key RSURLHVMZLSPCB-AUTFTWOTSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

991.1
MW (Da)
5.07
ALogP
19
HBA
1
HBD
233.4
PSA (Ų)
0.15
QED
3
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C51H74O19
MW 991.13
Aromatic Rings 0
Heavy Atoms 70
NP-Likeness 1.83

Activity Summary

IC50 1 meas. best 5.09

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
OVCAR-3
CHEMBL614213
IC50 5.09 5.09 8200.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
OVCAR-3 IC50 = 8200.0 nM 5.09 Cytotoxicity against human OVCAR3 cells after 72 hrs by CellTiter 96 Aqueous One... 32096998

Literature References

Data from ChEMBL 36 via Core Engine