Compound Detail
CHEMBL4643562
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Basic Information
| ChEMBL ID | CHEMBL4643562 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YBGUVUPWKZVPGJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
354.4
MW (Da)
4.02
ALogP
5
HBA
2
HBD
63.6
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta CHEMBL3979 | EC50 | 7.72 | 7.72 | 19.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta | EC50 | = | 19.0 | nM | 7.72 | Agonist activity at GAL4-DBD fused human PPARdelta (147 to 441 residues) express... | 32539376 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32539376 | 10.1021/acs.jmedchem.9b01882 | Peroxisome proliferator-activated receptor delta | 1 |
Data from ChEMBL 36 via Core Engine