Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL4644653

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(C(=O)NO)cc1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4644653
Phase Preclinical
Structure Type MOL
InChI Key ITCOJMPKEZPNDL-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

420.3
MW (Da)
4.40
ALogP
3
HBA
2
HBD
69.6
PSA (Ų)
0.44
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H14F6N2O3
MW 420.31
Aromatic Rings 2
Heavy Atoms 29
NP-Likeness -1.25

Literature References

PubMed DOI Target Context # Activities
32672458 10.1021/acs.jmedchem.0c01025 Histone deacetylase 3 1
32672458 10.1021/acs.jmedchem.0c01025 Histone deacetylase 6 1
32672458 10.1021/acs.jmedchem.0c01025 Histone deacetylase 8 1
32672458 10.1021/acs.jmedchem.0c01025 Histone deacetylase 11 1

Data from ChEMBL 36 via Core Engine