Compound Detail
CHEMBL465159
PINUSOLIDIC ACID Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL465159 |
| Name | PINUSOLIDIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FHQSDRHZGCMBKG-FIYPYCPBSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
10
Publications
0
Known Names
Molecular Properties
332.4
MW (Da)
4.11
ALogP
3
HBA
1
HBD
63.6
PSA (Ų)
0.62
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.33
IC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| SARS-CoV CHEMBL4303836 | EC50 | 5.33 | 5.33 | 4710.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| SARS-CoV | EC50 | = | 4710.0 | nM | 5.33 | Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibit... | 17663539 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17663539 | 10.1021/jm070295s | SARS-CoV | 5 |
| 15104493 | 10.1021/np034033e | Erythrocyte | 4 |
| 17663539 | 10.1021/jm070295s | Vero | 1 |
| 17663539 | 10.1021/jm070295s | Unchecked | 1 |
| 15104493 | 10.1021/np034033e | Plasmodium falciparum | 1 |
| 23691952 | 10.1021/np400010c | SW480 | 1 |
| 23691952 | 10.1021/np400010c | MCF7 | 1 |
| 23691952 | 10.1021/np400010c | A549 | 1 |
| 23691952 | 10.1021/np400010c | SMMC-7721 | 1 |
| 23691952 | 10.1021/np400010c | HL-60 | 1 |
Data from ChEMBL 36 via Core Engine