Compound Detail
CHEMBL469630
CAJANIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL469630 |
| Name | CAJANIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ALFNTRJPGFNJQV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names
Molecular Properties
300.3
MW (Da)
2.59
ALogP
6
HBA
3
HBD
100.1
PSA (Ų)
0.67
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MNT-1 CHEMBL5209890 | IC50 | 6.0 | 6.0 | 1000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MNT-1 | IC50 | = | 1000.0 | nM | 6.0 | Antiproliferative activity against human MNT-1 cells assessed as reduction in ce... | 39026645 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16038557 | 10.1021/np0580107 | Cladosporium cucumerinum | 3 |
| 16038557 | 10.1021/np0580107 | Radical scavenging activity | 3 |
| 16038557 | 10.1021/np0580107 | Candida albicans | 2 |
| 19124244 | 10.1016/j.bmcl.2008.12.064 | Osteoblast | 1 |
| 21265557 | 10.1021/np1005218 | Klebsiella pneumoniae | 1 |
| 21265557 | 10.1021/np1005218 | Staphylococcus aureus | 1 |
| 21265557 | 10.1021/np1005218 | Pseudomonas aeruginosa | 1 |
| 21265557 | 10.1021/np1005218 | Escherichia coli | 1 |
| 21265557 | 10.1021/np1005218 | Aspergillus niger | 1 |
| 21265557 | 10.1021/np1005218 | Candida albicans | 1 |
| 39026645 | 10.1039/d4md00224e | MNT-1 | 1 |
Data from ChEMBL 36 via Core Engine