Compound Detail
CHEMBL470267
FUSTIN Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL470267 |
| Name | FUSTIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNUPUYFWZXZMIE-LSDHHAIUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
288.2
MW (Da)
1.48
ALogP
6
HBA
4
HBD
107.2
PSA (Ų)
0.59
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.17 | 6.17 | 671.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 671.0 | nM | 6.17 | Inhibition of beef heart mitochondrial NADH oxidase assessed per mg of protein | 2959755 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2959755 | 10.1021/np50051a014 | Unchecked | 1 |
| 3379415 | 10.1021/np50056a030 | Xanthine dehydrogenase/oxidase | 1 |
| 1479375 | 10.1021/np50089a001 | Unchecked | 1 |
| 8882428 | 10.1021/np960057s | Monocyte | 1 |
| 2607357 | 10.1021/np50065a011 | Unchecked | 1 |
| - | 10.1007/s00044-007-9060-5 | Radical scavenging activity | 1 |
| 24630560 | 10.1016/j.bmcl.2014.02.039 | Aromatase | 1 |
| 28793973 | 10.1016/j.ejmech.2017.07.034 | K562 | 1 |
Data from ChEMBL 36 via Core Engine