Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL470647

LECANORIN
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1cc(O)cc(OC(=O)c2c(C)cc(O)cc2O)c1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL470647
Name LECANORIN
Phase Preclinical
Structure Type MOL
InChI Key LRMGCIMCOOHPQA-UHFFFAOYSA-N
0
Targets
6
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names

Molecular Properties

274.3
MW (Da)
2.64
ALogP
5
HBA
3
HBD
87.0
PSA (Ų)
0.58
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C15H14O5
MW 274.27
Aromatic Rings 2
Heavy Atoms 20
NP-Likeness 0.77

Activity Summary

IC50 6 meas.

Literature References

PubMed DOI Target Context # Activities
11076561 10.1021/np0001326 Unchecked 21
11076561 10.1021/np0001326 Amaranthus hypochondriacus 2
11076561 10.1021/np0001326 Echinochloa crus-galli 2
28129981 10.1016/j.bmcl.2017.01.032 Unchecked 1
28129981 10.1016/j.bmcl.2017.01.032 No relevant target 1
28181807 10.1021/acs.jnatprod.6b00465 HeLa 1
28181807 10.1021/acs.jnatprod.6b00465 HepG2 1
28181807 10.1021/acs.jnatprod.6b00465 NCI-H460 1
28181807 10.1021/acs.jnatprod.6b00465 MCF7 1

Data from ChEMBL 36 via Core Engine