Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL474122

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Nc1nc2c(CNC(CO)CO)c[nH]c2c(=O)[nH]1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL474122
Phase Preclinical
Structure Type MOL
InChI Key ODSSPGZQDUORCO-UHFFFAOYSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

253.3
MW (Da)
-1.72
ALogP
6
HBA
6
HBD
140.1
PSA (Ų)
0.37
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H15N5O3
MW 253.26
Aromatic Rings 2
Heavy Atoms 18
NP-Likeness -0.02

Activity Summary

Ki 2 meas.

Literature References

PubMed DOI Target Context # Activities
19170524 10.1021/jm801421q Purine nucleoside phosphorylase 1
38701712 10.1016/j.ejmech.2024.116437 Purine nucleoside phosphorylase 1

Data from ChEMBL 36 via Core Engine