Compound Detail
CHEMBL4743093
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4743093 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CXNAGUKJFXNYTN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
290.3
MW (Da)
2.17
ALogP
6
HBA
0
HBD
53.4
PSA (Ų)
0.64
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cathepsin Z CHEMBL4160 | IC50 | 5.02 | 5.02 | 9540.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cathepsin Z | IC50 | = | 9540.0 | nM | 5.02 | Inhibition of human cathepsin X expressed in Pichia pastoris assessed as residua... | 32208223 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32208223 | 10.1016/j.ejmech.2020.112218 | Cathepsin Z | 2 |
| 32208223 | 10.1016/j.ejmech.2020.112218 | PC-3 | 2 |
Data from ChEMBL 36 via Core Engine