Compound Detail
CHEMBL4752852
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4752852 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NTBGMDVYEDDYJR-MRXNPFEDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
395.8
MW (Da)
3.44
ALogP
5
HBA
1
HBD
60.0
PSA (Ų)
0.74
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Short transient receptor potential channel 6 CHEMBL2417347 | IC50 | 9.52 | 9.52 | 0.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Short transient receptor potential channel 6 | IC50 | = | 0.3 | nM | 9.52 | Inhibition of human TRPC6 channel transfected in HEK293 cells assessed as intrac... | 33738049 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33738049 | 10.1021/acsmedchemlett.1c00056 | Short transient receptor potential channel 6 | 1 |
Data from ChEMBL 36 via Core Engine