Compound Detail
CHEMBL477856
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Basic Information
| ChEMBL ID | CHEMBL477856 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AUYTYBXOQNJIFH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
364.4
MW (Da)
6.23
ALogP
2
HBA
0
HBD
17.8
PSA (Ų)
0.42
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fructose-1,6-bisphosphatase 1 CHEMBL5360 | IC50 | 5.22 | 5.22 | 6040.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fructose-1,6-bisphosphatase 1 | IC50 | = | 6040.0 | nM | 5.22 | Inhibition of fructose-1,6-bisphosphatase in mouse liver homogenates by colorime... | 19143528 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19143528 | 10.1021/jm800720a | Fructose-1,6-bisphosphatase 1 | 1 |
Data from ChEMBL 36 via Core Engine