Compound Detail
CHEMBL477935
GLAUCOGENIN C Enter ChEMBL ID:
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C[C@]12OC=C3CC[C@H]4[C@@H](CC=C5C[C@@H](O)CC[C@@]54C)C(=O)OC(CO1)[C@@H]32
Basic Information
| ChEMBL ID | CHEMBL477935 |
| Name | GLAUCOGENIN C |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZCEYOMXMDDYIQP-ZYQXTWTMSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
360.4
MW (Da)
3.08
ALogP
5
HBA
1
HBD
65.0
PSA (Ų)
0.53
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tobacco mosaic virus CHEMBL613818 | IC50 | 7.77 | 7.77 | 17.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tobacco mosaic virus | IC50 | = | 17.0 | nM | 7.77 | Inhibition of TMV U1 replication in tobacco BY2 protoplast by local lesion assay... | 17470783 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17470783 | 10.1073/pnas.0702398104 | Tobacco mosaic virus | 14 |
| 17470783 | 10.1073/pnas.0702398104 | Sindbis virus | 1 |
| 17470783 | 10.1073/pnas.0702398104 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine