Compound Detail
CHEMBL478589
GERANYLGERANIOL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL478589 |
| Name | GERANYLGERANIOL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OJISWRZIEWCUBN-QIRCYJPOSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names
Molecular Properties
290.5
MW (Da)
6.12
ALogP
1
HBA
1
HBD
20.2
PSA (Ų)
0.48
QED
1
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.65
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.65 | 4.53 | 22200.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 22200.0 | nM | 4.65 | Inhibition of wild-type HIV1 RT associated RNA dependent DNA polymerase activity... | 28254698 |
| Unchecked | IC50 | = | 39000.0 | nM | 4.41 | Inhibition of recombinant HIV-1 group M subtype B RT-RNase H activity expressed ... | 28254698 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30016091 | 10.1021/acs.jmedchem.8b00886 | RPMI-8226 | 4 |
| 28254698 | 10.1016/j.ejmech.2017.02.054 | Unchecked | 2 |
| 1522419 | 10.1021/np50084a012 | Corynebacterium ammoniagenes | 1 |
| 1522419 | 10.1021/np50084a012 | Bacillus subtilis | 1 |
| 1522419 | 10.1021/np50084a012 | Staphylococcus aureus | 1 |
| 1522419 | 10.1021/np50084a012 | Streptococcus mutans | 1 |
| 1522419 | 10.1021/np50084a012 | Cutibacterium acnes | 1 |
| 24641242 | 10.1021/np400872m | No relevant target | 1 |
| 33310291 | 10.1016/j.ejmech.2020.113062 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine