Compound Detail
CHEMBL4798660
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4798660 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WIBOODKYDGCRQM-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
405.5
MW (Da)
3.45
ALogP
4
HBA
2
HBD
91.0
PSA (Ų)
0.72
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cyclin-dependent kinase 12 CHEMBL3559692 | IC50 | 6.75 | 6.75 | 178.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cyclin-dependent kinase 12 | IC50 | = | 178.0 | nM | 6.75 | Inhibition of CDK12 (unknown origin) using ULight - 4E - BP1( Thr37 / Thr46 ) as... | - |
| Cyclin-dependent kinase 12 | IC50 | = | 178.0 | nM | 6.75 | Biochemical Assay for CDK12 (IC50 Determination): The inhibitory activity of the... | - |
Data from ChEMBL 36 via Core Engine