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Compound Detail

CHEMBL4802240

FOSCARBIDOPA
💊 Approved Drug
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💊 Approved Drug
C[C@@](Cc1ccc(OP(=O)(O)O)c(O)c1)(NN)C(=O)O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4802240
Name FOSCARBIDOPA
Phase Approved
Structure Type MOL
InChI Key PQUZXFMHVSMUNG-JTQLQIEISA-N
Active Moiety CHEMBL1200748

Known Names

ABBV-951 Carbidopa Carbidopa 4'-monophosphate Foscarbidopa Foscarbidopa component of abbv-951 Foscarbidopa component of vyalev
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
5
Known Names
1
Indications
1
Mechanisms

Molecular Properties

306.2
MW (Da)
-0.29
ALogP
6
HBA
6
HBD
162.3
PSA (Ų)
0.24
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
First Approval 2024
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

Prodrug
USAN Stem -dopa; fos-
USAN Year 2021

Extended Properties

Molecular Formula C10H15N2O7P
MW 306.21
Aromatic Rings 1
Heavy Atoms 20
NP-Likeness 0.78

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
DOPA decarboxylase inhibitor INHIBITOR Aromatic-L-amino-acid decarboxylase ✓ ✓

Indications

Parkinson Disease

Data from ChEMBL 36 via Core Engine