Compound Detail
CHEMBL480406
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Basic Information
| ChEMBL ID | CHEMBL480406 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ODJUOZPKKHIEOZ-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
284.4
MW (Da)
4.66
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.58 | 5.145 | 2600.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2600.0 | nM | 5.58 | Inhibition of rabbit skeletal muscle sarco/endoplasmic reticulum calcium ATPase ... | 23643898 |
| Unchecked | IC50 | = | 19500.0 | nM | 4.71 | Inhibition of rabbit hind leg tissue microsomes ATPase activity of SERCA assesse... | 19117760 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21353727 | 10.1016/j.ejmech.2011.01.069 | Unchecked | 2 |
| 19117760 | 10.1016/j.bmc.2008.12.010 | Unchecked | 1 |
| 23643898 | 10.1016/j.bmc.2013.04.012 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine