Compound Detail
CHEMBL4848974
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Basic Information
| ChEMBL ID | CHEMBL4848974 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MXGMFJSGIRRKKG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
313.8
MW (Da)
4.81
ALogP
1
HBA
2
HBD
53.1
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 9.42 | 9.42 | 0.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 1 | EC50 | = | 0.38 | nM | 9.42 | Agonist activity at GPR40 (unknown origin) expressed in CHO cells co-expressing ... | 33769827 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33769827 | 10.1021/acs.jmedchem.1c00031 | Free fatty acid receptor 1 | 2 |
| 33769827 | 10.1021/acs.jmedchem.1c00031 | Peroxisome proliferator-activated receptor gamma | 2 |
Data from ChEMBL 36 via Core Engine