Compound Detail
CHEMBL4856239
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4856239 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QVKLNBIURDBXIF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
473.6
MW (Da)
3.39
ALogP
8
HBA
1
HBD
104.7
PSA (Ų)
0.72
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glucose-dependent insulinotropic receptor CHEMBL5652 | EC50 | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glucose-dependent insulinotropic receptor | EC50 | = | 300.0 | nM | 6.52 | Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP... | 34010766 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34010766 | 10.1016/j.bmc.2021.116208 | Glucose-dependent insulinotropic receptor | 1 |
| 34010766 | 10.1016/j.bmc.2021.116208 | Voltage-gated inwardly rectifying potassium channel KCNH2 | 1 |
| 34010766 | 10.1016/j.bmc.2021.116208 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine