Compound Detail
CHEMBL485924
LATRUNCULIN C Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C/C1=C/C(=O)O[C@@H](CC(O)[C@@H]2CSC(=O)N2)C[C@H](O)CC[C@H](C)/C=C\CC1
Basic Information
| ChEMBL ID | CHEMBL485924 |
| Name | LATRUNCULIN C |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JDROCHDFKUSVDQ-CNUXZQNMSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
397.5
MW (Da)
2.94
ALogP
6
HBA
3
HBD
95.9
PSA (Ų)
0.50
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MDA-MB-435 CHEMBL614697 | IC50 | 4.46 | 4.46 | 34300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MDA-MB-435 | IC50 | = | 34300.0 | nM | 4.46 | Cytotoxicity against human MDA-MB-435 cells 48 hrs by SRB assay | 18942825 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18942825 | 10.1021/jm8008585 | MDA-MB-435 | 2 |
| 18942825 | 10.1021/jm8008585 | HCT-116 | 1 |
| 18942825 | 10.1021/jm8008585 | A10 | 1 |
Data from ChEMBL 36 via Core Engine