Compound Detail
CHEMBL4862698
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Basic Information
| ChEMBL ID | CHEMBL4862698 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RAOLSNCCCVWSHC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
393.4
MW (Da)
1.43
ALogP
8
HBA
1
HBD
145.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 CHEMBL4879430 | IC50 | 4.58 | 4.58 | 26180.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 | IC50 | = | 26180.0 | nM | 4.58 | Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in... | 34048880 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34048880 | 10.1016/j.bmcl.2021.128139 | Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 | 1 |
Data from ChEMBL 36 via Core Engine