Compound Detail
CHEMBL486600
DRACORHODIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL486600 |
| Name | DRACORHODIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UCZJPQIEFFTIEV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
266.3
MW (Da)
3.73
ALogP
3
HBA
0
HBD
39.4
PSA (Ų)
0.71
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.11 | 5.11 | 7700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 7700.0 | nM | 5.11 | Inhibition of porcine heart malate dehydrogenase preincubated for 5 min followed... | 34812616 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34812616 | 10.1021/acs.jmedchem.1c01547 | Unchecked | 3 |
| 7153779 | 10.1021/np50023a024 | Staphylococcus aureus | 1 |
| 7153779 | 10.1021/np50023a024 | Escherichia coli | 1 |
| 7153779 | 10.1021/np50023a024 | Salmonella enterica subsp. enterica serovar Gallinarum | 1 |
| 7153779 | 10.1021/np50023a024 | Klebsiella pneumoniae | 1 |
| 7153779 | 10.1021/np50023a024 | Mycolicibacterium smegmatis | 1 |
| 7153779 | 10.1021/np50023a024 | Candida albicans | 1 |
Data from ChEMBL 36 via Core Engine