Compound Detail
CHEMBL488738
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Basic Information
| ChEMBL ID | CHEMBL488738 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GLXMMOOGCALSDK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
412.4
MW (Da)
5.01
ALogP
4
HBA
1
HBD
39.7
PSA (Ų)
0.60
QED
1
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Extracellular calcium-sensing receptor CHEMBL1878 | IC50 | 6.02 | 6.02 | 950.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Extracellular calcium-sensing receptor | IC50 | = | 950.0 | nM | 6.02 | Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0... | 19492813 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19492813 | 10.1021/jm900364m | Extracellular calcium-sensing receptor | 1 |
| 19492813 | 10.1021/jm900364m | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine