Compound Detail
CHEMBL489406
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Basic Information
| ChEMBL ID | CHEMBL489406 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ICAMLTCIKCHCQB-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1185885 |
| Active Moiety | CHEMBL1185885 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
319.4
MW (Da)
3.27
ALogP
2
HBA
2
HBD
34.9
PSA (Ų)
0.57
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.99 | 4.99 | 10300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 10300.0 | nM | 4.99 | Inhibition of amplification of synthetic HTG21 telomere assessed as G-quadruplex... | 18821749 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18821749 | 10.1021/jm800497p | Unchecked | 3 |
Data from ChEMBL 36 via Core Engine