Compound Detail
CHEMBL494427
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Basic Information
| ChEMBL ID | CHEMBL494427 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OBCIEGQQVZKMIA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
439.6
MW (Da)
3.34
ALogP
5
HBA
1
HBD
61.9
PSA (Ų)
0.55
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.49
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | IC50 | 5.49 | 5.49 | 3241.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | IC50 | = | 3241.0 | nM | 5.49 | Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO ce... | 18456500 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18456500 | 10.1016/j.bmc.2008.04.023 | 5-hydroxytryptamine receptor 7 | 1 |
Data from ChEMBL 36 via Core Engine