Compound Detail
CHEMBL502979
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Basic Information
| ChEMBL ID | CHEMBL502979 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SUTPDSQFTVTPTM-VNYZMKMESA-N |
| Parent Compound | CHEMBL1187449 |
| Active Moiety | CHEMBL1187449 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
257.8
MW (Da)
4.07
ALogP
1
HBA
1
HBD
26.0
PSA (Ų)
0.88
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2C CHEMBL225 | EC50 | 5.8 | 5.8 | 1577.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | EC50 | = | 1577.0 | nM | 5.8 | Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as c... | 19284718 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19284718 | 10.1021/jm801354e | 5-hydroxytryptamine receptor 2B | 2 |
| 19284718 | 10.1021/jm801354e | 5-hydroxytryptamine receptor 2C | 2 |
| 19284718 | 10.1021/jm801354e | 5-hydroxytryptamine receptor 2A | 2 |
Data from ChEMBL 36 via Core Engine