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Compound Detail

CHEMBL503018

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CC(=O)OCO/N=[N+](\[O-])N1CCC[C@H]1C(=O)OCc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cc2)cc1

Basic Information

ChEMBL ID CHEMBL503018
Phase Preclinical
Structure Type MOL
InChI Key RDRARWPLGJTFMR-MRBOMJAESA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

625.6
MW (Da)
3.80
ALogP
11
HBA
0
HBD
155.5
PSA (Ų)
0.08
QED
2
Ro5 Violations
10
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H26F3N5O8S
MW 625.58
Aromatic Rings 3
Heavy Atoms 43
NP-Likeness -0.87

Literature References

PubMed DOI Target Context # Activities
18930406 10.1016/j.bmc.2008.10.001 Prostaglandin G/H synthase 1 1
18930406 10.1016/j.bmc.2008.10.001 Prostaglandin G/H synthase 2 1
18930406 10.1016/j.bmc.2008.10.001 Rattus norvegicus 1
18930406 10.1016/j.bmc.2008.10.001 No relevant target 1
18930406 10.1016/j.bmc.2008.10.001 ADMET 1

Data from ChEMBL 36 via Core Engine