Compound Detail
CHEMBL505747
GINSENOSIDE RG2 Enter ChEMBL ID:
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CC(C)=CCC[C@](C)(O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O)C(C)(C)[C@@H]3[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C[C@]12C
Basic Information
| ChEMBL ID | CHEMBL505747 |
| Name | GINSENOSIDE RG2 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AGBCLJAHARWNLA-DQUQINEDSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
785.0
MW (Da)
2.15
ALogP
13
HBA
9
HBD
219.0
PSA (Ų)
0.12
QED
3
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.6
IC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| No relevant target CHEMBL2362975 | EC50 | 4.6 | 4.6 | 25000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| No relevant target | EC50 | = | 25000.0 | nM | 4.6 | Reduction in surface tension in 0.1 M PBS after 10 mins by Wilhelmy plate method... | 22503361 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22503361 | 10.1016/j.bmc.2012.03.032 | ECV-304 | 2 |
| 22503361 | 10.1016/j.bmc.2012.03.032 | No relevant target | 2 |
| 2849641 | 10.1021/np50059a019 | Unchecked | 1 |
| 25442304 | 10.1016/j.bmcl.2014.09.087 | U-251 | 1 |
| 25442304 | 10.1016/j.bmcl.2014.09.087 | C6 | 1 |
| 29317167 | 10.1016/j.bmcl.2017.12.067 | NAD-dependent protein deacetylase sirtuin-1 | 1 |
Data from ChEMBL 36 via Core Engine