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Compound Detail

CHEMBL5085124

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COc1ccc(C[C@@H]2NC(=O)[C@H]([C@H](C)O)NC(=O)[C@@H]3[C@@H]4CCN3C(=O)[C@@H]3Cc5cn(c6ccc(F)cc56)Cc5cn(nn5)-c5cc(cc(c5)CSCCC(=O)N[C@@H](C)C(=O)N[C@@H](CNC(=O)CCOCCOCCNC(=O)CCCC[C@@H]5SC[C@H]6NC(=O)N[C@@H]56)C(=O)N[C@@H](Cc5cccc(c5)C/C=C/CO4)C(=O)N3)CSCCNC(=O)[C@]3(C)CCCN3C2=O)cc1

Basic Information

ChEMBL ID CHEMBL5085124
Phase Preclinical
Structure Type MOL
InChI Key DBHUWSCFNOUPCN-PRFVQGLSSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

1795.2
MW (Da)

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C88H112FN17O17S3
MW 1795.17

Activity Summary

Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
34704436 10.1021/acs.jmedchem.1c01599 Proprotein convertase subtilisin/kexin type 9 3

Data from ChEMBL 36 via Core Engine