Compound Detail
CHEMBL509374
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Basic Information
| ChEMBL ID | CHEMBL509374 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | OYUUVTJIINDYIH-ZCHJXOKKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
3197.7
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Calcitonin gene-related peptide 1 CHEMBL5293 | IC50 | 8.76 | 8.76 | 1.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Calcitonin gene-related peptide 1 | IC50 | = | 1.74 | nM | 8.76 | Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as e... | 19053766 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19053766 | 10.1021/jm8009298 | Calcitonin gene-related peptide 1 | 2 |
Data from ChEMBL 36 via Core Engine