Compound Detail
CHEMBL5095179
EZURPIMTROSTAT 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL5095179 |
| Name | EZURPIMTROSTAT |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | QVXSJSXAVQJXOV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
4
Known Names
4
Indications
Molecular Properties
423.0
MW (Da)
5.86
ALogP
4
HBA
2
HBD
40.2
PSA (Ų)
0.54
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Indications
Carcinoma, Hepatocellular Severe Acute Respiratory Syndrome Cholangiocarcinoma Liver Neoplasms
Activity Summary
IC50 1 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| LN-18 CHEMBL4296458 | IC50 | 6.66 | 6.66 | 220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| LN-18 | IC50 | = | 220.0 | nM | 6.66 | Antitumor activity against human LN-18 cells assessed as reduction in cell growt... | 38621327 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38621327 | 10.1016/j.ejmech.2024.116408 | LN-18 | 1 |
Data from ChEMBL 36 via Core Engine