Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5095474

EXAGAMGLOGENE AUTOTEMCEL
💊 Approved Drug
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL5095474
Name EXAGAMGLOGENE AUTOTEMCEL
Phase Approved
Structure Type NONE
Therapeutic ✓ Yes

Known Names

Casgevy CTX-001 CTX001 Exagamglogene autotemcel
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
4
Known Names
4
Indications
1
Mechanisms

Drug Information

Molecule Type Gene
First Approval 2023
Availability Unknown
Chirality Single Enantiomer
USAN Year 2022

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
B-cell lymphoma/leukemia 11A gene editing negative modulator GENE EDITING NEGATIVE MODULATOR B-cell lymphoma/leukemia 11A

Indications

Anemia, Sickle Cell beta-Thalassemia beta-Thalassemia Vaso-Occlusive Crises

ATC Classification

B06AX05
exagamglogene autotemcel
Level 1: BLOOD AND BLOOD FORMING ORGANS
Level 2: OTHER HEMATOLOGICAL AGENTS

Data from ChEMBL 36 via Core Engine